Article
Heterogeneity of HLA-DR4 in Greeks including a unique DR4-DQw2 association.
Tissue antigens - 1 Jan 1990
Awad J, Ollier W, Cutbush S, Papasteriadis C, Gupta A, Carthy D, McCloskey D, Brown C J, Boki K, Fostizopoulos G
Abstract excerpt
It has been shown that Greek RA patients do not show an increased frequency of HLA-DR4 compared with Greek controls. As only the Dw4 and Dw14 subtypes of DR4 are implicated in RA, we have characterised DR4-positive Greek RA patients and controls using serology, MLC typing and RFLP analysis to see whether the distribution of DR4 subtypes or other HLA antigens associated with DR4 could account for these findings....
Topics
- Arthritis, Rheumatoid
- Female
- Greece
- HLA-DQ Antigens
- HLA-DR4 Antigen
- Humans
- Male
- Pedigree
- Phenotype
- Polymorphism, Restriction Fragment Length