Article
The association of HLA DR beta alleles with self-limiting and persistent forms of early symmetrical polyarthritis.
British journal of rheumatology - 1 Jul 1993
Salmon M, Wordsworth P, Emery P, Tunn E, Bacon P A, Bell J I
Abstract excerpt
RA is associated with a group of class II DR beta alleles, which share a conserved sequence in the third allelic hypervariable region (3AHVR). These include the DR4 subtypes Dw4, Dw14 and Dw15, and also DR1. In contrast Dw10 and Dw13 which are also DR4 subtypes show no association with RA and have a quite distinct 3AHVR. We have assessed the frequency of these alleles in 55 patients who initially presented with...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.