Article
HLA antigens in Tlingit Indians with rheumatoid arthritis.
Tissue antigens - 1 Aug 1992
Nelson J L, Boyer G, Templin D, Lanier A, Barrington R, Nisperos B, Smith A, Mickelson E, Hansen J A
Abstract excerpt
HLA-DR4 has been described in association with rheumatoid arthritis (RA) in multiple populations. We have studied HLA antigens in Alaskan Tlingit Indians. HLA-DR4 was decreased in the RA group (n = 32) compared with controls (n = 62) (6% vs 21% p = 0.07). The predominant DR4 allele observed was DRB1*0403 (Dw13.1). The most striking observation in these studies was a marked predominance of the DRB1*1402 allele...
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