Article
TagSNP transferability and relative loss of variability prediction from HapMap to an admixed population.
Journal of biomedical science - 14 Aug 2009
Lins Tulio C, Abreu Breno S, Pereira Rinaldo W
Abstract excerpt
BACKGROUND: The application of a subset of single nucleotide polymorphisms, the tagSNPs, can be useful in capturing untyped SNPs information in a genomic region. TagSNP transferability from the HapMap dataset to admixed populations is of uncertain value due population structure, admixture, drift and recombination effects. In this work an empirical dataset from a Brazilian admixed sample was evaluated against the...
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