Evaluation of the SNP tagging approach in an independent population sample--array-based SNP discovery in Sami.

doi:10.1007/s00439-007-0379-2

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Article

Evaluation of the SNP tagging approach in an independent population sample--array-based SNP discovery in Sami.

Human genetics - 1 Sept 2007

Johansson Asa, Vavruch-Nilsson Veronika, Cox David R, Frazer Kelly A, Gyllensten Ulf

Abstract excerpt

Significant efforts have been made to determine the correlation structure of common SNPs in the human genome. One method has been to identify the sets of tagSNPs that capture most of the genetic variation. Here, we evaluate the transferability of tagSNPs between populations using a population sample of Sami, the indigenous people of Scandinavia. Array-based SNP discovery in a 4.4 Mb region of 28 phased copies of...

Topics

Chromosomes, Human, Pair 21
Databases, Genetic
Ethnicity
Gene Frequency
Genetic Variation
Haplotypes
Humans
Microsatellite Repeats
Oligonucleotide Array Sequence Analysis
Polymorphism, Single Nucleotide
Sweden

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Open in PubMed

Identifiers

PMID: 17554563
DOI: 10.1007/s00439-007-0379-2

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