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Article

Mutation of epidermal growth factor receptor is associated with MIG6 expression.

The FEBS journal - 1 Sept 2009

Nagashima Takeshi, Ushikoshi-Nakayama Ryoko, Suenaga Atsushi, Ide Kaori, Yumoto Noriko, Naruo Yoshimi, Takahashi Kaoru, Saeki Yuko, Taiji Makoto, Tanaka Hiroshi, Tsai Shih-Feng, Hatakeyama Mariko

Abstract excerpt

Controlled activation of epidermal growth factor receptor (EGFR) is systematically guaranteed at the molecular level; however, aberrant activation of EGFR is frequently found in cancer. Transcription induced by EGFR activation often involves the coordinated expression of genes that positively and negatively regulate the original signaling pathway; therefore, alterations in EGFR kinase activity may reflect changes...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19674104
DOI: 10.1111/j.1742-4658.2009.07220.x

Genes

EGFR
EGF
ERRFI1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

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Mutation of epidermal growth factor receptor is associated with MIG6 expression.PMID 19674104Read ↗

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Loss of MIG6 Accelerates Initiation and Progression of Mutant Epidermal Growth Factor Receptor-Driven Lung Adenocarcinoma.Semantic proximity Read ↗

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Mutations in Mig6 reduce inhibition of the epidermal growth factor receptor.Semantic proximity Read ↗

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