Article
Mutation of epidermal growth factor receptor is associated with MIG6 expression.
The FEBS journal - 1 Sept 2009
Nagashima Takeshi, Ushikoshi-Nakayama Ryoko, Suenaga Atsushi, Ide Kaori, Yumoto Noriko, Naruo Yoshimi, Takahashi Kaoru, Saeki Yuko, Taiji Makoto, Tanaka Hiroshi, Tsai Shih-Feng, Hatakeyama Mariko
Abstract excerpt
Controlled activation of epidermal growth factor receptor (EGFR) is systematically guaranteed at the molecular level; however, aberrant activation of EGFR is frequently found in cancer. Transcription induced by EGFR activation often involves the coordinated expression of genes that positively and...
Topics
- Adaptor Proteins, Signal Transducing
- Cell Line, Tumor
- ErbB Receptors
- Gene Expression Profiling
- Genes, erbB
- Humans
- Intracellular Signaling Peptides and Proteins
- Mutation
- Nerve Tissue Proteins
- Signal Transduction
- Transcription, Genetic
- Tumor Suppressor Proteins