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Article

Analysis of the epidermal growth factor receptor specific transcriptome: effect of receptor expression level and an activating mutation.

Journal of cellular biochemistry - 1 Oct 2005

Pedersen Mikkel W, Pedersen Nina, Damstrup Lars, Villingshøj Mette, Sønder Søren U, Rieneck Klaus, Bovin Lone F, Spang-Thomsen Mogens, Poulsen Hans S

Abstract excerpt

Overexpression or expression of activating mutations of the epidermal growth factor receptor (EGFR) is common in cancer and correlates with neoplastic progression. The present study employed Affymetrix oligonucleotide arrays to profile genes induced by ligand-activated EGFR with the receptor either moderately expressed or overexpressed at an in-itself transforming level. These changes were compared to those...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16075456
DOI: 10.1002/jcb.20554

Genes

EGFR
STAT1
STAT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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