Article
IL-10 and TNF-alpha promoter haplotypes are associated with childhood Crohn's disease location.
World journal of gastroenterology - 14 Aug 2009
Sanchez Rocio, Levy Emile, Costea Florin, Sinnett Daniel
Abstract excerpt
AIM: To determine the distribution and frequencies of the genotypes and haplotypes of the genes encoding for the glucocorticoid receptor (GR), the tumor necrosis factor (TNF)-alpha and the interleukin (IL)-10 in childhood Crohn's disease (CD) and to assess the impact of the corresponding DNA variants on clinical and disease phenotypes. METHODS: Ten variants in GR, TNF-alpha and IL-10 were genotyped in 113...
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