Article
Interleukin 10 and tumor necrosis factor-alpha genotypes in rheumatoid arthritis--association with clinical response to glucocorticoids.
The Journal of rheumatology - 1 Mar 2010
de Paz Banesa, Alperi-López Mercedes, Ballina-García Francisco J, Prado Catuxa, Mozo Lourdes, Gutiérrez Carmen, Suárez Ana
Abstract excerpt
OBJECTIVE: There are dysregulated levels of interleukin 10 (IL-10) and tumor necrosis factor-alpha (TNF-alpha) in rheumatoid arthritis (RA), and their role in the disease is controversial. We analyzed the association of functional polymorphisms of IL-10 and TNF-alpha with susceptibility and disease characteristics at the time of diagnosis, and we also evaluated their possible use as predictors of clinical...
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