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Article

Meta-analysis: polymorphisms in TNF-alpha gene promoter and Crohn's disease.

Alimentary pharmacology & therapeutics - 1 Jul 2010

Han Z, Li C, Han S, Han Y, Qiu J, Shi Y, Wang J, Sun A, Ding J, Wu K, Fan D

Abstract excerpt

BACKGROUND: Tumour necrosis factor alpha (TNF-alpha) is involved in the pathogenesis of Crohn's disease (CD). However, results on the association between the polymorphisms in TNF-alpha promoter and the risk of CD are inconsistent. AIM: To perform a quantitative synthesis for the genetic polymorphisms in TNF-alpha promoter and CD risk. METHODS: Databases were searched (up to 2009) and 31 studies were included....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20456305
DOI: 10.1111/j.1365-2036.2010.04340.x

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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