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Article

Association of polymorphisms in the IL-10 promoter region with Crohn's disease.

Journal of clinical laboratory analysis - 1 Dec 2022

Sun Anna, Li Wei, Shang Shiqiang

Abstract excerpt

BACKGROUND: IL-10 is thought to play an important role in preventing inflammatory bowel disease (IBD), although its efficacy is limited in IBD inflammation treatment. The purpose of this study is to investigate the association between SNP polymorphism in the promoter region of the IL-10 gene and Crohn's disease (CD). METHODS: In 86 children with CD disease and 142 healthy controls, polymorphisms of three SNPs...

Topics

Child
Humans
Interleukin-10
Crohn Disease
Genetic Predisposition to Disease
Gene Frequency
Polymorphism, Single Nucleotide
Haplotypes
Genotype
Inflammatory Bowel Diseases
Promoter Regions, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Case-Control Studies

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Identifiers

PMID: 36408729
DOI: 10.1002/jcla.24780
PMCID: PMC9757008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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