Article
Interleukin 10 promoter region polymorphisms in inflammatory bowel disease in Tunisian population.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] - 1 Mar 2009
Marrakchi R, Moussa A, Ouerhani S, Bougatef K, Bouhaha R, Messai Y, Rouissi K, Khadimallah I, Khodjet-el-Khil H, Najar T, Benammar-Elgaaeid A
Abstract excerpt
OBJECTIVE: To test whether IL-10 promoter region polymorphisms are associated with susceptibility to inflammatory bowel disease, we examined the contribution of interleukin- 10 (IL-10) gene polymorphisms to Crohn's disease (CD) and Ulcerative colitis disease (UC) occurrence and also to CD phenotype. MATERIELS AND METHODS: SNPs at positions -627 (C > A) and -1117 (G > A) in the IL-10 promoter were determined in a...
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