Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cytokine Tumor Necrosis Factor‐alpha A Promoter Gene Polymorphism at Position −308 G→A and Pediatric Inflammatory Bowel Disease

1 May 2006

Abstract excerpt

OBJECTIVES: Our pilot study aimed to determine the effect of tumor necrosis factor-alpha (TNF-alpha) 308 G-->A promoter single-nucleotide polymorphism in pediatric inflammatory bowel disease (IBD), its influence on inflammatory activity and the clinical manifestations. METHODS: We obtained genomic DNA from 164 subjects, 82 with long-standing IBD aged 8 to 18 years: 46 with Crohn disease (CD) and 36 with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Immune Response and Inflammation
Share to Inflammatory Bowel Disease
Share to Rheumatoid Arthritis Research and Therapies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 16707968
DOI: 10.1097/01.mpg.0000221917.80887.9e

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cytokine Tumor Necrosis Factor‐alpha A Promoter Gene Polymorphism at Position −308 G→A and Pediatric Inflammatory Bowel DiseasePMID 16707968Read ↗

Role of tumor necrosis factor-alpha (C-863A) polymorphism in pathogenesis of inflammatory bowel disease in Northern India.Semantic proximity Read ↗

Tumour necrosis factor-alpha (-308G/A) promoter polymorphism is associated with ulcerative colitis in Brazilian patients.Semantic proximity Read ↗

Evaluation of tumor necrosis factor (TNF)-α mRNA expression level and the rs1799964 polymorphism of the TNF-α gene in peripheral mononuclear cells of patients with inflammatory bowel diseasesSemantic proximity Read ↗

Inflammatory bowel disease: the role of inflammatory cytokine gene polymorphisms.Semantic proximity Read ↗

Evaluation of TNF alpha G308A promoter gene polymorphism and serum TNF alpha levels in patients with inflammatory bowel disease in Turkish populationSemantic proximity Read ↗

IL-10 and TNF-alpha promoter haplotypes are associated with childhood Crohn's disease location.Semantic proximity Read ↗

Single nucleotide polymorphism in the tumor necrosis factor-alpha gene affects inflammatory bowel diseases risk.Semantic proximity Read ↗

Tumor necrosis factor-α -308 A/G gene polymorphism in children with juvenile idiopathic arthritis: relation to disease activity, damage, and functional status.Semantic proximity Read ↗

Meta-analysis: polymorphisms in TNF-alpha gene promoter and Crohn's disease.Semantic proximity Read ↗

Tumor necrosis factor-alpha -308 genotypes influence inflammatory activity and TNF-alpha serum concentrations in children with juvenile idiopathic arthritis.Semantic proximity Read ↗

TNF-α -308 G > A (rs1800629) Polymorphism is Associated with Celiac Disease: A Meta-analysis of 11 Case-Control Studies.Semantic proximity Read ↗

Polymorphisms of tumor necrosis factor-alpha but not MDR1 influence response to medical therapy in pediatric-onset inflammatory bowel disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.