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Article

Blocking the salt-inducible kinase 1 network prevents the increases in cell sodium transport caused by a hypertension-linked mutation in human alpha-adducin.

Journal of hypertension - 1 Dec 2009

Stenström Karin, Takemori Hiroshi, Bianchi Giuseppe, Katz Adrian I, Bertorello Alejandro M

Abstract excerpt

OBJECTIVES: Because a newly described salt-inducible kinase 1 (SIK1) network is responsible for increases in active cell sodium transport in response to elevated intracellular sodium, we hypothesized that this network could mediate the effects of the mutant (hypertensive) form of alpha-adducin on...

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Source

Identifiers

PMID: 19657284
DOI: 10.1097/HJH.0b013e328330cf15

Genes

SIK1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19657284-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Blocking the salt-inducible kinase 1 network prevents the increases in cell sodium transport caused by a hypertension-linked mutation in human alpha-adducin.PMID 19657284Read ↗

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