Article
Modulation of Na(+)-K(+)-ATPase cell surface abundance through structural determinants on the α1-subunit.
American journal of physiology. Cell physiology - 1 Jan 2011
Pierre Sandrine V, Belliard Aude, Sottejeau Yoann
Abstract excerpt
Through their ion-pumping and non-ion-pumping functions, Na(+)-K(+)-ATPase protein complexes at the plasma membrane are critical to intracellular homeostasis and to the physiological and pharmacological actions of cardiotonic steroids. Alteration of the abundance of Na(+)-K(+)-ATPase units at the cell surface is one of the mechanisms for Na(+)-K(+)-ATPase regulation in health and diseases that has been closely...
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