Article
Molecular and structural basis of steroid hormone binding and release from corticosteroid-binding globulin.
Molecular and cellular endocrinology - 5 Mar 2010
Lin Hai-Yan, Muller Yves A, Hammond Geoffrey L
Abstract excerpt
Corticosteroid-binding globulin (CBG), a non-inhibitory member of the serine proteinase inhibitor (serpin) super-family, is the high-affinity transport protein for glucocorticoids in vertebrate blood. Plasma CBG is a glycoprotein with 30% of its mass represented by N-linked oligosaccharide chains. Its well-characterized steroid-binding properties represent a "bench-mark data set" used extensively for in silico...
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