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The LRRK2 G2385R variant is a risk factor for sporadic Parkinson's disease in the Korean population.

Parkinsonism & related disorders - 1 Feb 2010

Kim Jong-Min, Lee Jee-Young, Kim Hee Jin, Kim Ji Seon, Shin Eun-Soon, Cho Jin-Hwan, Park Sung Sup, Jeon Beom S

Abstract excerpt

The G2385R (SNP accession no. rs34778348) and R1628P (rs33949390) variants of leucine-rich repeat kinase 2 (LRRK2, PARK8) are emerging as an important risk factor for Parkinson's disease (PD) in the ethnic Chinese and Japanese populations. The purpose of this study was to investigate whether these variants are a genetic risk factor in sporadic PD patients in the Korean population. A total of 923 patients and 422...

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PMID: 19854095
DOI: 10.1016/j.parkreldis.2009.10.004

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The LRRK2 G2385R variant is a risk factor for sporadic Parkinson's disease in the Korean population.PMID 19854095Read ↗

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LRRK2 Gly2385Arg variant is a risk factor of Parkinson's disease among Han-Chinese from mainland China.Semantic proximity Read ↗

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The prevalence of LRRK2 Gly2385Arg variant in Chinese Han population with Parkinson's disease.Semantic proximity Read ↗

LRRK2 low-penetrance mutations (Gly2019Ser) and risk alleles (Gly2385Arg)-linking familial and sporadic Parkinson's disease.Semantic proximity Read ↗

LRRK2 G2385R and R1628P mutations are associated with an increased risk of Parkinson's disease in the Malaysian population.Semantic proximity Read ↗

Identification of a common genetic risk variant (LRRK2 Gly2385Arg) in Parkinson's disease.Semantic proximity Read ↗

Comprehensive mutational analysis of LRRK2 reveals variants supporting association with autosomal dominant Parkinson's disease.Semantic proximity Read ↗

A common missense variant in the LRRK2 gene, Gly2385Arg, associated with Parkinson's disease risk in Taiwan.Semantic proximity Read ↗

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