Article
Analysis of the LRRK2 Gly2385Arg variant in primary dystonia and multiple system atrophy in Taiwan.
Parkinsonism & related disorders - 1 Jan 2008
Lu Chin-Song, Chang Hsiu-Chen, Weng Yi-Hsin, Chen Rou-Shayn, Bonifati Vincenzo, Wu-Chou Yah-Huei
Abstract excerpt
The c.G7153A variant in the LRRK2 gene (protein effect: Gly2385Arg) is emerging as an important risk factor for Parkinson's disease (PD) in the Han Chinese and Japanese populations. The prevalence of this variant in other neurodegenerative diseases and movement disorders remains almost completely unexplored. Using MALDI-TOF, we studied the Gly2385Arg variant in a large cohort of patients with primary dystonia...
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