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Article

[Role of SV40 T antigen binding sites within the 5' flanking region of human U1 and U2 snRNA genes].

Shi yan sheng wu xue bao - 1 Dec 1990

Han Y M

Abstract excerpt

The 5' flanking regions of the genes encoding human U1 and U2 snRNA each contain multiple copies of consensus pentanucleotide 5' GA/GGGC 3' which bind specifically to the SV40 T antigen. To examine the role of T antigen binding sites, the mutants deleted and substituted the pentanucleotide sequences from 5' flanking of U1 and U2 genes were constructed by oligonucleotide-directed DNA synthesis. A similar...

Topics

Animals
Antigens, Polyomavirus Transforming
Antigens, Viral, Tumor
Base Sequence
Binding Sites
Humans
Molecular Sequence Data
Mutation
RNA, Small Nuclear
Repetitive Sequences, Nucleic Acid
Simian virus 40

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Transcription, Genetic

Transfection

Xenopus laevis

rRNA Operon

Source

Identifiers

PMID: 1963523

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1963523-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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