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Article

Expression of a human 7S K RNA gene in vivo requires a novel pol III upstream element.

The EMBO journal - 1 Mar 1990

Kleinert H, Bredow S, Benecke B J

Abstract excerpt

The 5'-flanking sequences required for expression of a human 7S K RNA gene have been defined by mutant analysis. A -111 upstream deletion mutant showed full activity when analysed by in vitro transcription with HeLa cell extracts. In contrast, upon transfection into intact cells, this mutant only revealed a basal level activity of approximately 6% as compared to the wild-type promoter up to position -252. The...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 2138077
DOI: 10.1002/j.1460-2075.1990.tb08164.x
PMCID: PMC551725

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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