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Article

Site-directed mutational analysis of a U4 small nuclear RNA gene proximal sequence element. Localization and identification of functional nucleotides.

The Journal of biological chemistry - 15 Jun 1990

McNamara K J, Stumph W E

Abstract excerpt

The genes that encode the small nuclear RNAs (snRNAs) are unusual RNA polymerase II transcription units in that 5'-flanking DNA sequences more than 50 base pairs upstream of snRNA genes are essential for specifying the transcription initiation site. The relevant cis-acting DNA sequence, termed th...

Topics

Animals
Base Sequence
Cell Nucleus
Chickens
Cloning, Molecular
Female
Genes
Molecular Sequence Data
Mutation
Oocytes
RNA Polymerase II
RNA, Small Nuclear

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Restriction Mapping

Templates, Genetic

Transcription, Genetic

Xenopus laevis

Source

Identifiers

PMID: 2351667

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2351667-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Site-directed mutational analysis of a U4 small nuclear RNA gene proximal sequence element. Localization and identification of functional nucleotides.PMID 2351667Read ↗

Identification of proximal sequence element nucleotides contributing to the differential expression of variant U4 small nuclear RNA genes.Semantic proximity Read ↗

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