Article
U2 and U1 snRNA gene loci associate with coiled bodies.
Journal of cellular biochemistry - 1 Dec 1995
Smith K P, Carter K C, Johnson C V, Lawrence J B
Abstract excerpt
The coiled bodies are nuclear structures rich in a variety of nuclear and nucleolar components including snRNAs. We have investigated the possibility that coiled bodies may associate with snRNA genes and report here that there is a high degree of association between U2 and U1 genes with a subset of coiled bodies. As investigated in human HeLa cells grown in monolayer culture, about 75% of nuclei had at least one...
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