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Article

Parent-of-origin of HLA-DRB1*1501 and age of onset of multiple sclerosis.

Journal of human genetics - 1 Sept 2009

Ramagopalan Sreeram V, Byrnes Jake K, Dyment David A, Guimond Colleen, Handunnetthi Lahiru, Disanto Giulio, Yee Irene M, Ebers George C, Sadovnick A Dessa

Abstract excerpt

Multiple sclerosis (MS) is a complex neurological trait. Allelic variation in the MHC class II region exerts the single strongest effect on MS genetic risk. The clinical onset of the disease is extremely variable, and can range from the first to the ninth decade of life. Epidemiological studies h...

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Source

Identifiers

PMID: 19629136
DOI: 10.1038/jhg.2009.69

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19629136-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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