Article
Folate/homocysteine phenotypes and MTHFR 677C>T genotypes are associated with serum levels of monocyte chemoattractant protein-1.
Clinical immunology (Orlando, Fla.) - 1 Oct 2009
Hammons Andrea L, Summers Carolyn M, Woodside Jayne V, McNulty Helene, Strain J J, Young Ian S, Murray Liam, Boreham Colin A, Scott John M, Mitchell Laura E, Whitehead Alexander S
Abstract excerpt
Monocyte chemoattractant protein-1 (MCP-1) is a chemokine that recruits monocytes into the subendothelial cell layer in atherosclerotic lesions. Elevated homocysteine (hyperhomocysteinemia), which is usually associated with low-folate status, is a known risk factor for many pathologies with inflammatory etiologies. The present study was undertaken to examine whether there are associations between MCP-1...
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