Article
Serum total homocysteine, folate, 5,10-methylenetetrahydrofolate reductase (MTHFR) 677C-->T genotype and subclinical atherosclerosis.
Expert opinion on therapeutic targets - 1 Jan 2009
Panayiotou Andrie, Nicolaides Andrew, Griffin Maura, Tyllis Theodosis, Georgiou Niki, Martin Richard M, Bond Dawn, Tziakouri-Shiakalli Chrysa, Fessas Charis, Deltas Constantinos
Abstract excerpt
OBJECTIVE: To determine the relationship of serum total homocysteine (tHcy), serum folate and 5,10-methylenetetrahydrofolate reductase (MTHFR) 677C-->T genotype with ultrasonic arterial wall measurements associated with subclinical atherosclerosis. STUDY DESIGN: Cross-sectional analysis of 767 participants in an ongoing prospective study. Intima-media thickness (IMT) of the common carotid (IMTcc), IMT of the...
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