Article
Methionine synthase reductase 66A->G polymorphism is associated with increased plasma homocysteine concentration when combined with the homozygous methylenetetrahydrofolate reductase 677C->T variant.
The Journal of nutrition - 1 Nov 2004
Vaughn Jaimie D, Bailey Lynn B, Shelnutt Karla P, Dunwoody Kristina M von-Castel, Maneval David R, Davis Steven R, Quinlivan Eoin P, Gregory Jesse F, Theriaque Douglas W, Kauwell Gail P A
Abstract excerpt
Methylenetetrahydrofolate reductase (MTHFR) and methionine synthase reductase (MTRR) are important for homocysteine remethylation. This study was designed to determine the influence of genetic variants (MTHFR 677C-->T, MTHFR 1298A-->C, and MTRR 66A-->G), folate, and vitamin B-12 status on plasma...
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