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Article

Low folate levels may be an atherogenic factor regardless of homocysteine levels in young healthy nonsmokers.

Metabolism: clinical and experimental - 1 May 2010

Imamura Akiko, Murakami Ryuichiro, Takahashi Ryotaro, Cheng Xian Wu, Numaguchi Yasushi, Murohara Toyoaki, Okumura Kenji

Abstract excerpt

Low folate and high homocysteine levels are emerging as important risk factors for atherosclerosis and predictors of early coronary heart disease. We evaluated folate and homocysteine levels, compared them with endothelial function, and analyzed their association with the methylenetetrahydrofolate reductase (MTHFR) and endothelial nitric oxide synthase genotypes. We recruited 71 young healthy male nonsmokers...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19913857
DOI: 10.1016/j.metabol.2009.09.017

Genes

MTHFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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