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Article

The relationship between homocysteine and genes of folate-related enzymes in migraine patients.

Headache - 1 Jan 2010

Oterino Agustin, Toriello Maria, Valle Natalia, Castillo Jesus, Alonso-Arranz Ana, Bravo Yolanda, Ruiz-Alegria Carlos, Quintela Estrella, Pascual Julio

Abstract excerpt

BACKGROUND: It has been suggested that homocysteine (Hcy) and the 5'-10'-methylenetetrahydrofolate reductase (MTHFR) C677T variant are implicated in the pathogenesis of migraine. Homocysteine has the potential to damage endothelium and accelerate atherosclerosis. Genetic factors such as the MTHFR C677T polymorphism, and other polymorphisms in folate-related genes associated with high homocysteine levels, may...

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Share to Epigenesis, Genetic
Share to Folic Acid

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Methylenetetrahydrofolate Reductase (NADPH2)

Share to Migraine Disorders

Share to Migraine with Aura

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Share to Thymidylate Synthase

Source

Identifiers

PMID: 19619240
DOI: 10.1111/j.1526-4610.2009.01484.x

Genes

MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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The relationship between homocysteine and genes of folate-related enzymes in migraine patients.PMID 19619240Read ↗

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Relation between Methylenetetrahydrofolate Reductase C677T and A1298C Polymorphisms and Migraine SusceptibilitySemantic proximity Read ↗

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