Article
Association of variants of the interleukin-23 receptor gene with susceptibility to pediatric Crohn's disease.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association - 1 Aug 2007
Baldassano Robert N, Bradfield Jonathan P, Monos Dimitri S, Kim Cecilia E, Glessner Joseph T, Casalunovo Tracy, Frackelton Edward C, Otieno F George, Kanterakis Stathis, Shaner Julie L, Smith Ryan M, Eckert Andrew W, Robinson Luke J, Onyiah Chioma C, Abrams Debra J, Chiavacci Rosetta M, Skraban Robert, Devoto Marcella, Grant Struan F A, Hakonarson Hakon
Abstract excerpt
BACKGROUND & AIMS: Recently an association was shown between the single nucleotide polymorphism (SNP), rs11209026, within the interleukin-23 receptor (IL23R) locus and Crohn's disease (CD) as a consequence of a genome-wide association study of this disease in adults. We examined the effects of th...
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