Article
Susceptibility loci reported in genome-wide association studies are associated with Crohn's disease in Canadian children.
Alimentary pharmacology & therapeutics - 1 Jun 2010
Amre D K, Mack D R, Morgan K, Israel D, Deslandres C, Seidman E G, Lambrette P, Costea I, Krupoves A, Fegury H, Dong J, Grimard G, Levy E
Abstract excerpt
BACKGROUND: Recent genome-wide association studies based on adult and paediatric populations have implicated >30 genes/loci as susceptibility loci for Crohn's disease (CD). AIMS: To investigate whether reported genes/loci were also associated with CD in Canadian children. DESIGN AND METHODS: A case-control design was implemented at three paediatric gastroenterology clinics in Canada. Children < or =18 years of...
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