Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Role of the CYP2D6, EPHX1, MPO, and NQO1 genes in the susceptibility to acute lymphoblastic leukemia in Brazilian children.

Environmental and molecular mutagenesis - 1 Jan 2010

Silveira Vanessa da Silva, Canalle Renata, Scrideli Carlos Alberto, Queiroz Rosane Gomes de Paula, Tone Luiz Gonzaga

Abstract excerpt

Polymorphic variations of several genes associated with dietary effects and exposure to environmental carcinogens may influence susceptibility to leukemia development. The objective of the present study was to evaluate the effect of the polymorphisms of debrisoquine hydroxylase (CYP2D6), epoxide hydrolase (EPHX1), myeloperoxidase (MPO), and quinone-oxoreductase (NQO1), which have been implicated in xenobiotic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Brazil

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cytochrome P-450 CYP2D6

Share to Genetic Predisposition to Disease

Share to Infant

Share to Precursor Cell Lymphoblastic Leukemia-Lymphoma

Share to Recombinant Fusion Proteins

Share to Recombinant Proteins

Source

Identifiers

PMID: 19593802
DOI: 10.1002/em.20510

Genes

EPHX1
MPO
NQO1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Role of the CYP2D6, EPHX1, MPO, and NQO1 genes in the susceptibility to acute lymphoblastic leukemia in Brazilian children.PMID 19593802Read ↗

Role of NQO1, MPO and CYP2E1 genetic polymorphisms in the susceptibility to childhood acute lymphoblastic leukemia.Semantic proximity Read ↗

Polymorphisms in genes encoding drugs and xenobiotic metabolizing enzymes, DNA repair enzymes, and response to treatment of childhood acute lymphoblastic leukemia.Semantic proximity Read ↗

NQO1 rs1800566 (C609T), PON1 rs662 (Q192R), and PON1 rs854560 (L55M) polymorphisms segregate the risk of childhood acute leukemias according to age range distribution.Semantic proximity Read ↗

Genotype-Environment Interaction Analysis of NQO1, CYP2E1, and NAT2 Polymorphisms and the Risk of Childhood Acute Lymphoblastic Leukemia: A Report From the Mexican Interinstitutional Group for the Identification of the Causes of Childhood LeukemiaSemantic proximity Read ↗

Childhood acute lymphoblastic leukemia: genetic determinants of susceptibility and disease outcome.Semantic proximity Read ↗

Role of CYP2D6, CYP1A1, CYP2E1, GSTT1, and GSTM1 genes in the susceptibility to acute leukemias.Semantic proximity Read ↗

Genetic polymorphisms of NQO1, CYP1A1 and TPMT and susceptibility to acute lymphoblastic leukemia in a Tunisian population.Semantic proximity Read ↗

CYP2B6 gene single nucleotide polymorphisms and leukemia susceptibility.Semantic proximity Read ↗

Genetic polymorphisms and susceptibility to childhood acute lymphoblastic leukemia.Semantic proximity Read ↗

Impact of NQO1, GSTM1 and GSTT1 genetic variants on susceptibility and relapse in childhood acute lymphoblastic leukemia.Semantic proximity Read ↗

Childhood Pre-B acute lymphoblastic leukemia and glutathione S-transferase omega 1 and 2 polymorphisms.Semantic proximity Read ↗

No association between cytochrome P450 2D6 gene polymorphism and risk of acute leukemia: evidence based on a meta-analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.