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Article

Role of the CYP2D6, EPHX1, MPO, and NQO1 genes in the susceptibility to acute lymphoblastic leukemia in Brazilian children.

Environmental and molecular mutagenesis - 1 Jan 2010

Silveira Vanessa da Silva, Canalle Renata, Scrideli Carlos Alberto, Queiroz Rosane Gomes de Paula, Tone Luiz Gonzaga

Abstract excerpt

Polymorphic variations of several genes associated with dietary effects and exposure to environmental carcinogens may influence susceptibility to leukemia development. The objective of the present study was to evaluate the effect of the polymorphisms of debrisoquine hydroxylase (CYP2D6), epoxide...

Topics

Adolescent
Brazil
Cytochrome P-450 CYP2D6
Epoxide Hydrolases
Female
Genetic Predisposition to Disease
Granulocyte Colony-Stimulating Factor
Humans
Infant
Interleukin-3
Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

NAD(P)H Dehydrogenase (Quinone)

Precursor Cell Lymphoblastic Leukemia-Lymphoma

Recombinant Fusion Proteins

Recombinant Proteins

Source

Identifiers

PMID: 19593802
DOI: 10.1002/em.20510

Genes

EPHX1
MPO
NQO1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-19593802-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Role of the CYP2D6, EPHX1, MPO, and NQO1 genes in the susceptibility to acute lymphoblastic leukemia in Brazilian children.PMID 19593802Read ↗

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