Childhood Pre-B acute lymphoblastic leukemia and glutathione S-transferase omega 1 and 2 polymorphisms.

doi:10.1111/ijlh.12332

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Article

Childhood Pre-B acute lymphoblastic leukemia and glutathione S-transferase omega 1 and 2 polymorphisms.

International journal of laboratory hematology - 1 Aug 2015

Rezazadeh D, Moradi M-T, Kazemi A, Mansouri K

Abstract excerpt

INTRODUCTION: Acute lymphoblastic leukemia (ALL) is the most prevalent malignancy among children and makes up 23% of total childhood cancers worldwide. Pre-B ALL is one of the most common ALLs, comprising about 80% of childhood cases. A variety of genes are involved in metabolizing carcinogens. These gene polymorphisms can result in less efficient or overly-down metabolic pathways, which may contribute to the...

Topics

Adolescent
Alleles
Case-Control Studies
Child
Female
Gene Frequency
Genotype
Glutathione Transferase
Heterozygote
Homozygote
Humans
Male
Odds Ratio
Polymorphism, Genetic
Precursor B-Cell Lymphoblastic Leukemia-Lymphoma

Source

Open in PubMed

Identifiers

PMID: 25726706
DOI: 10.1111/ijlh.12332

Genes

GSTO1
GSTO2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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