Article
No association between cytochrome P450 2D6 gene polymorphism and risk of acute leukemia: evidence based on a meta-analysis.
Chinese medical journal - 1 Jan 2013
Ruan Xiao-lan, Li Sheng, Zeng Xian-tao, Xia Ling-hui, Hu Yu
Abstract excerpt
BACKGROUND: Many studies indicated the human cytochrome P450 2D6 (CYP2D6) gene polymorphism was associated with acute leukemia (AL) susceptibility, however, the results were inconsistent. So we performed this meta-analysis to evaluate the relationship between CYP2D6*3 or CYP2D6*4 polymorphism and AL susceptibility. METHODS: We searched PubMed database up to February 20, 2013, and finally yielded 9 case-control...
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