No association between cytochrome P450 2D6 gene polymorphism and risk of acute leukemia: evidence based on a meta-analysis.

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Article

No association between cytochrome P450 2D6 gene polymorphism and risk of acute leukemia: evidence based on a meta-analysis.

Chinese medical journal - 1 Jan 2013

Ruan Xiao-lan, Li Sheng, Zeng Xian-tao, Xia Ling-hui, Hu Yu

Abstract excerpt

BACKGROUND: Many studies indicated the human cytochrome P450 2D6 (CYP2D6) gene polymorphism was associated with acute leukemia (AL) susceptibility, however, the results were inconsistent. So we performed this meta-analysis to evaluate the relationship between CYP2D6*3 or CYP2D6*4 polymorphism and AL susceptibility. METHODS: We searched PubMed database up to February 20, 2013, and finally yielded 9 case-control...

Topics

Acute Disease
Cytochrome P-450 CYP2D6
Genetic Predisposition to Disease
Humans
Leukemia
Polymorphism, Genetic
Risk

Source

Open in PubMed

Identifiers

PMID: 24112176

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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