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Article

Genetic polymorphisms and susceptibility to childhood acute lymphoblastic leukemia.

Environmental and molecular mutagenesis - 1 Jan 2004

Canalle Renata, Burim Regislaine V, Tone Luiz G, Takahashi Catarina S

Abstract excerpt

Acute lymphoblastic leukemia (ALL) is the most common form of pediatric cancer. Although exposure to environmental agents appears to predispose individuals to this disease, little attention has been paid to the role of genetic susceptibility to environmental exposures in the etiology of childhood ALL. The enzymes GSTM1, GSTT1, GSTP1, CYP1A1, and CYP2E1 are involved in the bioactivation and detoxification of a...

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Identifiers

PMID: 14991750
DOI: 10.1002/em.20003

Genes

GSTM1
GSTP1
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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