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Article

MIF (macrophage migration inhibitory factor) promoter polymorphisms and susceptibility to severe malarial anemia.

The Journal of infectious diseases - 15 Aug 2009

Awandare Gordon A, Martinson Jeremy J, Were Tom, Ouma Collins, Davenport Gregory C, Ong'echa John M, Wang Wenkui, Leng Lin, Ferrell Robert E, Bucala Richard, Perkins Douglas J

Abstract excerpt

BACKGROUND: Severe malarial anemia (SMA) resulting from Plasmodium falciparum infection is one of the leading causes of childhood mortality in sub-Saharan Africa. The innate immune mediator macrophage migration inhibitory factor (MIF) plays a critical role in the pathogenesis of SMA. METHODS: To investigate the influence of MIF genetic variation on susceptibility to SMA, haplotypes of the MIF -173G/C and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19591577
DOI: 10.1086/600894
PMCID: PMC3607439

Genes

MIF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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