Article
A critical role for the host mediator macrophage migration inhibitory factor in the pathogenesis of malarial anemia.
The Journal of experimental medicine - 15 May 2006
McDevitt Michael A, Xie Jianlin, Ganapathy-Kanniappan Shanmugasundaram, Shanmugasundaram Ganapathy, Griffith Jason, Liu Aihua, McDonald Courtney, Thuma Philip, Gordeuk Victor R, Metz Christine N, Mitchell Robert, Keefer Jeffrey, David John, Leng Lin, Bucala Richard
Abstract excerpt
The pathogenesis of malarial anemia is multifactorial, and the mechanisms responsible for its high mortality are poorly understood. Studies indicate that host mediators produced during malaria infection may suppress erythroid progenitor development (Miller, K.L., J.C. Schooley, K.L. Smith, B. Kul...
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