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Article

Functional haplotypes of Fc gamma (Fcγ) receptor (FcγRIIA and FcγRIIIB) predict risk to repeated episodes of severe malarial anemia and mortality in Kenyan children.

Human genetics - 1 Feb 2012

Ouma Collins, Davenport Gregory C, Garcia Steven, Kempaiah Prakasha, Chaudhary Ateefa, Were Tom, Anyona Samuel B, Raballah Evans, Konah Stephen N, Hittner James B, Vulule John M, Ong'echa John M, Perkins Douglas J

Abstract excerpt

Development of protective immunity against Plasmodium falciparum is partially mediated through binding of malaria-specific IgG to Fc gamma (γ) receptors. Variations in human FcγRIIA-H/R-131 and FcγRIIIB-NA1/NA2 affect differential binding of IgG sub-classes. Since variability in FcγR may play an...

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Identifiers

PMID: 21818580
DOI: 10.1007/s00439-011-1076-8
PMCID: PMC3258363

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21818580-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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