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Article

Allele frequency of thiopurine methyltransferase and inosine triphosphate pyrophosphatase gene polymorphisms in Korean patients with inflammatory bowel diseases.

Hepato-gastroenterology - 1 Jan 2000

Cheon Jae Hee, Kim Jae Hak, Kim Bo Young, Kim Seung Won, Hong Sung Yi, Eun Chang Soo, Hong Seong Soo, Byeon Jeong-Sik, Kim Tae Il, Han Dong Soo, Yang Suk-Kyun, Lee Kyoung Ryul, Kim Won Ho

Abstract excerpt

BACKGROUND/AIMS: Adverse reactions to thiopurines may be predisposed by thiopurine methyltransferase (TPMT) or inosine triphosphate pyrophosphatase (ITPA) gene mutations. METHODOLOGY: We examined the frequencies of TPMT and ITPA gene polymorphisms in 812 Korean patients with inflammatory bowel diseases using denaturing high performance liquid chromatography and direct sequencing. RESULTS: The allele frequencies...

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Share to Azathioprine
Share to Chromatography, High Pressure Liquid

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19579612

Genes

TPMT
ITPA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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