Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Polymorphisms of the TPMT gene in the Czech healthy population and patients with inflammatory bowel disease.

Nucleosides, nucleotides & nucleic acids - 1 Jun 2008

Slanar Ondrej, Bortlík Martin, Buzková Helena, Donoval Robert, Pechandová Kristina, Sebesta Ivan, Lukás Milan, Perlík Frantisek

Abstract excerpt

Genetic variation in thiopurine S-methyltransferase (TPMT) is a major factors for wide variation in the metabolism and safety of thiopurine drugs. We investigated the frequency of functional gene polymorphisms in 396 patients with inflammatory bowel disease and 300 healthy subjects. Frequencies o...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Azathioprine
Share to Case-Control Studies
Share to Czech Republic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Frequency

Share to Health

Share to Inflammatory Bowel Diseases

Share to Methyltransferases

Share to Polymorphism, Genetic

Source

Identifiers

PMID: 18600549
DOI: 10.1080/15257770802146478

Genes

TPMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18600549-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polymorphisms of the TPMT gene in the Czech healthy population and patients with inflammatory bowel disease.PMID 18600549Read ↗

Thiopurine S-Methyltransferase gene polymorphisms in a healthy Slovak population and pediatric patients with inflammatory bowel disease.Semantic proximity Read ↗

AN EPIDEMIOLOGICAL STUDY OF THIOPURINE-METHYLTRANSFERASE VARIANTS IN A CROATIAN INFLAMMATORY BOWEL DISEASE PATIENT COHORT.Semantic proximity Read ↗

Pyrosequencing of TPMT alleles in a general Swedish population and in patients with inflammatory bowel disease.Semantic proximity Read ↗

Prevalence of thiopurine S-methyltransferase gene polymorphisms in patients with inflammatory bowel disease from the island of Crete, Greece.Semantic proximity Read ↗

Clinical pharmacogenomics of thiopurine S-methyltransferase.Semantic proximity Read ↗

Prevalence of mutations in thiopurine S-methyltransferase gene among Slovak IBD patients.Semantic proximity Read ↗

Prevalence of mutations in thiopurine S-methyltransferase gene among Slovak IBD patients.Semantic proximity Read ↗

Thiopurine methyltransferase gene polymorphisms in Chinese patients with inflammatory bowel disease.Semantic proximity Read ↗

Risk factors for thiopurine-induced myelosuppression and infections in inflammatory bowel disease patients with a normal TPMT genotype.Semantic proximity Read ↗

Analysis of thiopurine S-methyltransferase phenotype-genotype in a Tunisian population with Crohn's disease.Semantic proximity Read ↗

Should thiopurine methyltransferase genotypes and phenotypes be measured before thiopurine therapy in patients with inflammatory bowel disease?Semantic proximity Read ↗

Thiopurine-methyltransferase variants in inflammatory bowel disease: prevalence and toxicity in Brazilian patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.