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Article

Thiopurine-methyltransferase variants in inflammatory bowel disease: prevalence and toxicity in Brazilian patients.

World journal of gastroenterology - 28 Mar 2014

Carvalho Ana Teresa P, Esberard Barbara C, Fróes Renata S B, Rapozo Davy C M, Grinman Ana B, Simão Tatiana A, Santos Juliana C V C, Carneiro Antonio José V, Ribeiro-Pinto Luis Felipe, de Souza Heitor S P

Abstract excerpt

AIM: To analyze the prevalence of thiopurine-methyltransferase (TPMT) genotypes and their association with drug toxicity in inflammatory bowel disease (IBD) patients from southeastern Brazil. METHODS: A total of 219 consecutive patients with IBD, of which 146 had Crohn's disease and 73 had ulcerative colitis, regularly seen at the outpatient unit of the Division of Gastroenterology at the University Hospital...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24696613
DOI: 10.3748/wjg.v20.i12.3327
PMCID: PMC3964403

Genes

TPMT

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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