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Article

Thiopurine methyltransferase gene polymorphisms in Chinese patients with inflammatory bowel disease.

Digestion - 1 Jan 2009

Cao Qian, Zhu Qin, Shang Yan, Gao Min, Si Jianmin

Abstract excerpt

BACKGROUND: The thiopurine drugs azathioprine and 6-mercaptopurine are well established in the treatment of inflammatory bowel disease (IBD). However, great interpatient variability exists in the efficacy and toxicity of the drugs, and this results from thiopurine methyltransferase (TPMT) gene polymorphisms. The aim of this study was to identify the TPMT gene polymorphisms in Chinese IBD patients and to study the...

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Source

Identifiers

PMID: 19252404
DOI: 10.1159/000205268

Genes

TPMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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