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Article

Allele frequency of inosine triphosphate pyrophosphatase (ITPA) and thiopurine-S-methyl transferase (TPMT) genes in the Tunisian population.

Clinics and research in hepatology and gastroenterology - 1 Apr 2012

Melaouhia Salma, Fékih Monia, Garat Anne, Allorge Delphine, Ferchichi Henda, Klouz Anis, Boubaker Jalel, Broly Franck, Lakhal Mohamed

Abstract excerpt

AIM: The aim of this study was to determine the frequencies of TPMT and ITPA polymorphisms in Crohn's disease patients of Tunisian origin and to compare them with allele frequencies previously reported in other populations of various ethnic origins. METHODS: ITPA (c.94C>A and IVS2+21A>C) and TPMT (c.238G>C, c.460G>A and c.719A>G) mutations and genotypes were assessed in 208 Tunisian subjects (78 males/130...

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Source

Identifiers

PMID: 22225964
DOI: 10.1016/j.clinre.2011.12.001

Genes

ITPA
TPMT

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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