Article
Molecular phylogeny, long-term evolution, and functional divergence of flavin-containing monooxygenases.
Genetica - 1 Nov 2009
Hao Da Cheng, Chen Shi Lin, Mu Jun, Xiao Pei Gen
Abstract excerpt
Flavin-containing monooxygenases (FMOs) metabolize xenobiotic compounds, many of which are clinically important, as well as endogenous substrates as part of a discrete physiological process. The FMO gene family is conserved and ancient with representatives present in all phyla so far examined. However, there is a lack of information regarding the long-term evolution and functional divergence of these proteins....
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