Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Flavin-containing monooxygenases: mutations, disease and drug response.

Trends in pharmacological sciences - 1 Jun 2008

Phillips Ian R, Shephard Elizabeth A

Abstract excerpt

Flavin-containing monooxygenases (FMOs) metabolize numerous foreign chemicals, including drugs, pesticides and dietary components and, thus, mediate interactions between humans and their chemical environment. We describe the mechanism of action of FMOs and insights gained from the structure of yeast FMO. We then concentrate on the three FMOs (FMOs 1, 2 and 3) that are most important for metabolism of foreign...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alcoholism and Thiamine Deficiency
Share to Folate and B Vitamins Research
Share to FMO3 gene

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mutation

Share to Oxygenases

Share to Pharmaceutical Preparations

Share to Polymorphism, Genetic

Share to Schizosaccharomyces

Source

Identifiers

PMID: 18423897
DOI: 10.1016/j.tips.2008.03.004

Genes

FMO2
FMO3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Flavin-containing monooxygenases: mutations, disease and drug response.PMID 18423897Read ↗

Flavin-containing monooxygenase 3 and human disease.Semantic proximity Read ↗

Survey of variants of human flavin-containing monooxygenase 3 (FMO3) and their drug oxidation activities.Semantic proximity Read ↗

Flavin-containing monooxygenase genetic polymorphism: impact on chemical metabolism and drug development.Semantic proximity Read ↗

Identification and functional analysis of common human flavin-containing monooxygenase 3 genetic variants.Semantic proximity Read ↗

Flavin-containing monooxygenase 3 (FMO3): genetic variants and their consequences for drug metabolism and diseaseSemantic proximity Read ↗

Mutation, polymorphism and perspectives for the future of human flavin-containing monooxygenase 3.Semantic proximity Read ↗

Human flavin-containing monooxygenases.Semantic proximity Read ↗

Human flavin-containing monooxygenase (form 3): polymorphisms and variations in chemical metabolism.Semantic proximity Read ↗

Drug metabolism by flavin-containing monooxygenases of human and mouse.Semantic proximity Read ↗

Trimethylaminuria and a human FMO3 mutation database.Semantic proximity Read ↗

Mutations of the flavin-containing monooxygenase gene (FMO3) cause trimethylaminuria, a defect in detoxication.Semantic proximity Read ↗

Molecular evolution and balancing selection in the flavin-containing monooxygenase 3 gene (FMO3).Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.