Article
Role of ATG16L1 Thr300Ala polymorphism in inflammatory bowel disease: a Study in the Spanish population and a meta-analysis.
Inflammatory bowel diseases - 1 Nov 2009
Márquez Ana, Núñez Concepción, Martínez Alfonso, Mendoza Juan Luis, Taxonera Carlos, Fernández-Arquero Miguel, Díaz-Rubio Manuel, de la Concha Emilio G, Urcelay Elena
Abstract excerpt
BACKGROUND: Thr300Ala polymorphism in ATG16L1 was reported as a susceptibility factor to Crohn's disease (CD). Inconsistently replicated associations with ulcerative colitis (UC) and specifically with ileal CD were also reported. Our aims were: to replicate the ATG16L1 Thr300Ala association with inflammatory bowel disease (IBD) in the Spanish population, to perform a meta-analysis to determine the risk conferred...
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