ATG16L1 T300A polymorphism and Crohn's disease susceptibility: evidence from 13,022 cases and 17,532 controls.

doi:10.1007/s00439-009-0660-7

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Article

ATG16L1 T300A polymorphism and Crohn's disease susceptibility: evidence from 13,022 cases and 17,532 controls.

Human genetics - 1 Jun 2009

Zhang Hai-Feng, Qiu Li-Xin, Chen Yu, Zhu Wa-Li, Mao Chen, Zhu Li-Guang, Zheng Ming-Hua, Wang Yan, Lei Lei, Shi Jian

Abstract excerpt

Many studies have reported the association between the autophagy-related 16-like 1 gene (ATG16L1) T300A polymorphism (rs2241880) and Crohn's disease (CD) susceptibility, but the results were inconclusive. To derive a more precise estimation of the relationship, a meta-analysis was performed. A total of 24 studies including 13,022 cases and 17,532 controls were included in this meta-analysis. Logistic regression...

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PMID: 19337756
DOI: 10.1007/s00439-009-0660-7

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