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Article

T300A genetic polymorphism: a susceptibility factor for Crohn's disease?

Arquivos de gastroenterologia - 1 Jan 2000

Scolaro Bruno Lorenzo, dos Santos Emily, Ferreira Leslie Ecker, França Paulo Henrique Condeixa de, Kleinubing Harry, Kotze Paulo Gustavo, Pinho Mauro de Souza Leite

Abstract excerpt

CONTEXT: Crohn's disease is characterized by a chronic and debilitating inflammatory disorder of the gastrointestinal tract. Several factors may contribute to its development. From extensive studies of the human genome, the polymorphism T300A of the gene ATG16L1 (autophagy-related 16-like 1) has been related to increased risk of developing this disease. OBJECTIVES: Analyze the role of polymorphism T300A...

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PMID: 25003259
DOI: 10.1590/s0004-28032014000200005

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T300A genetic polymorphism: a susceptibility factor for Crohn's disease?PMID 25003259Read ↗

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