Article
Association of IL23R p.381Gln and ATG16L1 p.197Ala with Crohn disease in the Czech population.
Journal of pediatric gastroenterology and nutrition - 1 Oct 2009
Dusatkova Petra, Hradsky Ondrej, Lenicek Martin, Bronsky Jiri, Nevoral Jiri, Kotalova Radana, Bajerova Katerina, Vitek Libor, Lukas Milan, Cinek Ondrej
Abstract excerpt
OBJECTIVES: An association of variants in the genes encoding the interleukin 23 receptor (IL23R, p.Arg381Gln, rs11209026), and the autophagy-related gene 16-like 1 (ATG16L1, p.Ala197Thr, rs2241880) with Crohn disease (CD) was identified by whole genome association studies, and subsequently confirmed by other works. The aim of this study was to assess this association in the Czech population. SUBJECTS AND METHODS:...
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