Article
The association between MC1R genotype and BRAF mutation status in cutaneous melanoma: findings from an Australian population.
The Journal of investigative dermatology - 1 Jan 2010
Hacker Elke, Hayward Nicholas K, Dumenil Troy, James Michael R, Whiteman David C
Abstract excerpt
There is increasing epidemiological and molecular evidence that cutaneous melanomas arise through multiple causal pathways. The purpose of this study was to explore the relationship between germline and somatic mutations in a population-based series of melanoma patients to reshape and refine the divergent pathway model for melanoma. Melanomas collected from 123 Australian patients were analyzed for melanocortin-1...
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