Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Inherited variation at MC1R and histological characteristics of primary melanoma.

PloS one - 1 Jan 2015

Taylor Nicholas J, Busam Klaus J, From Lynn, Groben Pamela A, Anton-Culver Hoda, Cust Anne E, Begg Colin B, Dwyer Terence, Gallagher Richard P, Gruber Stephen B, Orlow Irene, Rosso Stefano, Thomas Nancy E, Zanetti Roberto, Rebbeck Timothy R, Berwick Marianne, Kanetsky Peter A

Abstract excerpt

Variation in the melanocortin-1receptor (MC1R) gene is associated with pigmentary phenotypes and risk of malignant melanoma. Few studies have reported on MC1R variation with respect to tumor characteristics, especially clinically important prognostic features. We examined associations between MC1R variants and histopathological melanoma characteristics. Study participants were enrolled from nine geographic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genotype
Share to Genetic Association Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Melanoma

Share to Polymorphism, Single Nucleotide

Share to Receptor, Melanocortin, Type 1

Share to Risk Factors

Share to Skin Neoplasms

Share to Skin Pigmentation

Source

Open in PubMed Open full text

Identifiers

PMID: 25790105
DOI: 10.1371/journal.pone.0119920
PMCID: PMC4366050

Genes

GEM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Inherited variation at MC1R and histological characteristics of primary melanoma.PMID 25790105Read ↗

MC1R genotypes and risk of melanoma before age 40 years: a population-based case-control-family study.Semantic proximity Read ↗

MC1R variants as melanoma risk factors independent of at-risk phenotypic characteristics: a pooled analysis from the M-SKIP projectSemantic proximity Read ↗

Population-based study of natural variation in the melanocortin-1 receptor gene and melanoma.Semantic proximity Read ↗

Melanocortin 1 receptor and risk of cutaneous melanoma: a meta-analysis and estimates of population burden.Semantic proximity Read ↗

MC1R genotype as a predictor of early-onset melanoma, compared with self-reported and physician-measured traditional risk factors: an Australian case-control-family study.Semantic proximity Read ↗

A large French case-control study emphasizes the role of rare Mc1R variants in melanoma risk.Semantic proximity Read ↗

MC1R variants and cutaneous melanoma risk according to histological type, body site, and Breslow thickness: a pooled analysis from the M-SKIP project.Semantic proximity Read ↗

Contributions by MC1R Variants to Melanoma Risk in Males and Females.Semantic proximity Read ↗

Melanocortin receptor 1 variants and melanoma risk: a study of 2 European populations.Semantic proximity Read ↗

Melanocortin 1 receptor variants and their association with phenotypic characteristics and sporadic multiple primary melanomas in a cohort of 402 Spanish subjects.Semantic proximity Read ↗

Does MC1R genotype convey information about melanoma risk beyond risk phenotypes?Semantic proximity Read ↗

MC1R gene variants and non-melanoma skin cancer: a pooled-analysis from the M-SKIP project.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.